2nd Pan-amercian Conference for Alternative Methods

Date: August 23-24, 2018
Venue: Rua Ferreira Viana, 81 – Flamengo, Rio de Janeiro, in front of Windsor Florida Hotel (Casarão)

Starting in 2016 in Baltimore, now 2018 in Rio and planned for 2020 in Canada, the series Pan-American Conference for Alternative Methods brings South, Central, and North America together to further alternatives to animal testing and build collaboration for the exchange of scientific ideas.

The event was held in an innovative, low-investment format in which participants bear their participation costs. It should be noted that the participants, for the most part, are group leaders and experts in the field, being an event of high scientific and technological content.

The 2nd Pan American Conference for Alternative Methods will be held on August 23 and 24, 2018, in Rio de Janeiro, promoting the union of South, Central and North America to promote alternatives to animal testing and to build collaborations for the exchange scientists.

Participating in this event will be researchers from all over Brazil, as well as representatives from the pharmaceutical, cosmetic, pesticide and nanotechnology industry.

Call for Abstracts:

Deadline for Submission Extended to May 30th, 2018

Details and Registration:





The agenda will be released soon. We are compiling all abstracts for the scientific committee to review. The focus of the program will be the 6 Rs (see below).

The 6Rs:

  1. Replacement (3 sessions planned) – in vitro and in silico including organo-typic cultures and mechanistic toxicology (Tox-21c)
  2. Refinement –  best practices including non-invasive methods
  3. Reduction – approaches including assay integration, minimal change formulations, green toxicology
  4. Read-across – read-across and related in silico approaches – advances and challenges
  5. Relevance – ethical and economical views, quality aspects such as good cell culture practice, evidence-based toxicology, in vitro / in silico reporting standards
  6. Roadmaps – how to move the field? Communication, conferences, policy programs, stakeholder engagement

Themes proposal:

  • Cosmetics – Roundtable with researchers from cosmetics industries
  • Read Across – Filling the gap of information on systemic toxicology and allergy
  • In vitro/In vivo Extrapolation- Multiscale modeling approaches for assessing cosmetic ingredients safety
  • Fragrances
  • Agrochemicals
  • Drugs
  • Education
  • NGOs and 3Rs initiatives
  • Human-on-a-Chip
  • Evidence-based toxicology
  • Induced pluripotent stem cells (IPSCs)