Samuel Pessoa Conference
Alejandro Miguel Katzin (ICB-USP, Brazil)
Title: Biosynthesis of isoprenoids in Plasmodium falciparum
Closing Conference
Carlos Renato Machado (UFMG, Brazil)
Title: DNA metabolism in trypanosomatids: why so many differences?
CONFERENCES
1. Frédéric Bringaud (Université de Bordeaux, France)
Title: Glycerol metabolism as a novel regulator of trypanosome development and transmission
2. Mark Field (University of Dundee, UK)
Title: Benzoxaboroles target CPSF3 for degradation through a SUMO-dependent pathway in trypanosomes
3. Maria Belen Cassera (UGA, USA)
Title: From parasite biology to therapy: druggable targets in malaria.
4. Guillermo Alonso (INGEBI-UBA, Argentina)
Title: Energy status as a signal for adaptation and differentiation in Trypanosoma cruzi
5. Rubem Menna Barreto (IOC-FIOCRUZ – Brazil)
Title: Mitochondrial butterfly effect: how changes in the organelle physiology impacts the fitness of trypanosomatids
6. Calvin Tiengwe (Imperial College London, UK)
Title: The sweet side of immune evasion in African trypanosomes
7. Gerald Spaeth (Institut Pasteur – Paris, France)
Title: Genomic merger: How Leishmania hybridization drives parasite evolution and immune escape
8. Ana Beatriz Barletta (NIH/NIAID, USA)
Title: Mosquito midgut response to blood feeding at a single-cell resolution
9. Daniel Youssef Bargieri (ICB/USP, Brazil)
Title: TRAMP-CSS complex is essential for hepatocyte and erythrocyte infection by Plasmodium zoites
10. Daniel Inaoka (School of Tropical Medicine and Global Health – Nagasaki University, Japan)
Title: Trypanosomal acetate: succinate CoA transferase: from biochemical and structural characterization to a metabolic engineering tool for bioenergetic studies across organisms.
ROUND-TABLES
1. Mechanisms of Genomic Plasticity in Trypanosomatids
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- Lucy Glover (Institut Pasteur, France) – Title: From development to transmission: Understanding the development regulation of trypanosomes in the tsetse fly
- Richard McCulloch (University of Glasgow, UK) – Title: Deciphering the machineries that guide initiation and progression of nuclear DNA replication in Trypanosoma brucei
- Luiz Tosi (FMRP-USP, Brazil) – Title: The Cost of Flexibility: Mapping Replication Stress Hotspots and their Impact on Leishmania Genomic maintenance
- Daniella Bartholomeu (UFMG, Brazil) – Title: Mechanisms of Genomic Plasticity in Trypanosomatids
2. Vectors
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- Maisa da Silva Araujo (Fiocruz-Rondônia, Brazil) – Title: Effect of Anopheles midgut microbiota bacteria on the sexual development of Plasmodium vivax in Anopheles darlingi
- Isabela Barbosa Ramos (UFRJ, Brazil) – Title: Vitellogenin Receptor Function Shapes Fertility and Microbial Inheritance in Rhodnius prolixus
- Claudia Ríos Velasquez (Fiocruz-AM, Brazil) – Title: Trypanosomatids from the Brazilian Amazon: Invertebrate (dipterans) and vertebrate (didelphimorphs, rodents, anurans, squamates) hosts
- Erich Telleria (Charles University, República Tcheca) – Title: Sand fly immunity and gut receptors – implications for Leishmania infection in the vector
3. Diversity, Ecology and Evolution of Protists
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- Felipe Machado (NUPELIA-UEM, Brazil) – Title: Exploring the Hidden World of Protozooplankton in a Neotropical Floodplain: Advances, Current Challenges and Future Perspectives
- Gabriela Kuppers (MACN-CONICET, Argentina) – Title: A trait-based approach in ciliate functional ecology: toward a standardized framework
- Laura Utz (PUC-RS, Brazil) – Title: Diversity of microbial communities in aquatic and terrestrial environments
- Luana Morais (UNICAMP, SP, Brazil) – Title: Escaping Ice and Animals: Did Snowball Earth and the Rise of Metazoans Drive Testate Amoebae into Continental Waters?
4. Immunity to Trypanosoma cruzi in the Americas
- Luisa Mourão Dias Magalhães (UFMG, Brazil) – Title: How Trypanosoma cruzi Diversity Shapes Human Immune Responses
- Cristina Alonso-Vega (Universidad de Oviedo, Spain)– Title: From Fundamental Research to Public Health: Congenital Chagas in Bolivia
- Juliana Gomes Estanislau (UFMG, Brazil) – Title: Cellular and Molecular Biomarkers of Cardiac Remodeling: Insights from the Brazilian Scenario of Chagas Cardiomyopathy
- Eva Acosta Rodriguez (Universidad Nacional de Cordoba, Argentina) – Title: Stage-dependent adaptation of regulatory T cells during Trypanosoma cruzi infection
5. One Health
- Marcia Sperança (UFABC, Brazil) – Title: Detection of silent circulation of parasites to ecoepidemiology investigations in a One Health perspective
- Liam Morrison (University of Edinburgh, UK) – Title: Insights into trypanosome infection biology from the bovine model
- Aline Diniz Cabral (FCM/Santa Casa de SP, Brazil) – Title: Zoonotic sarcocystidae: challenges for One Health in protozoology
- Alec Evans (GalvMed, UK) – Title: The Fly That Shaped a Continent: African Trypanosomosis and the Evolution of One Health Solutions
6. Drivers of Diversity: Kinases, Translation, and the Evolution of Cell Populations
- Zdenek Paris (Institute of Parasitology, Czech Republic) – Title: Translational Tricks and Trypanosome Tactics
- Tiago Ferreira (FMRP-USP, Brazil) – Title: Gene expression programs driving Leishmania differentiation and transmission in the sand fly
- Simone Calderano (Butantan Institute, Brazil) – Title: Cell Cycle Regulation in Trypanosoma cruzi: Conserved Kinases with Parasite-Specific Functions
- Miguel Chiurillo (University of Cincinnati, USA) – Title: The NEK family in Trypanosoma cruzi: focus on RDK2 in differentiation and host–parasite interaction
16h30 – 17h00 | Opening Ceremony | Room A
17h00 – 18h00 | Opening Conference – Samuel Pessoa Award | Room A
Chair: Walter Colli
Biosynthesis of isoprenoids in Plasmodium falciparum
Alejandro Miguel Katzin (ICB-USP, Brazil)
18h00 – 19h00 | Brainstorm | Room B
Chair:
19h30 – 20h30 | Dinner
20h30 – 22h30 | Poster Session – ODD/Ímpares | GYMNASIUM
09h00 – 11h00 | Oral Presentations
OP.01 – Oral Presentations 01| ROOM A
Chairs:
PV001 – Roles of NFS, ISD11 and MTU1 in Mitochondrial tRNA Thiolation and Fe-S Clusters in Trypanosoma cruzi
Marilene Souza Braga (USP, Brazil)
HP001 – Cellular Senescence Integrates Inflammatory And Cytotoxic Axes In The Pathological Landscape Of Cutaneous Leishmaniasis
Paola De Oliveira Lopes (UFES, Brazil)
HP002 – Congenital Toxoplasma gondii infection alters dopaminergic pathway gene expression during retinal development.
Gustavo Pinheiro De Araujo (Fiocruz-RJ, Brazil)
TB001 – High-content screening of FDA-approved drugs in combination with benznidazole identifies potential anti – Trypanosoma cruzi agents.
Laura Maria Alcântara (USP, Brazil)
HP003 – Genomic Similarities Between Plasmodium simium and A Historical Sample Of Plasmodium From The Sado Valley, Portugal
Nathalia Rammé Medeiros De Albuquerque (USP, Brazil)
PV002 – Investigating a Likely Role for RBP43 in Regulating Expression of the Trypanosoma brucei Respiratome and Mediated through an Interaction with an Alternative Translation Initiation Complex
Savio Silas Farias Falcão (Fiocruz-PE, Brazil)
HP004 – Toxoplasma gondii alters mitochondrial dynamics in brain endothelial cells and cortical microvessels during early infection
Guilherme Andrade De Santana (Fiocruz-RJ, Brazil)
TB002 – Beyond Homology: Unveiling the Unique Structural Features of Trypanosoma cruzi ?-Glutamyl Phosphate Reductase
Maria Eduarda Souza Dias Lino (USP, Brazil)
OP.02 – Oral Presentations 02 | ROOM B
Chairs:
HP005 – Functional characterization of mercaptopyruvate sulfurtransferase supports a role in stress adaptation and host-cell infection in Trypanosoma cruzi
Jessica Jenireth Rodriguez Duran (USP, Brazil)
HP006 – Conserved mitochondrial and translational repression and strain-associated chromatin responses in Toxoplasma gondii-infected neuroblasts
Thuany Prado Rangel Marcelo (Fiocruz-RJ, Brazil)
PV003 – Identification of genes potentially involved in vector competence in Nyssomyia umbratilis from endemic and non-endemic areas for american tegumentary leishmaniasis in the amazon region.
Victor Ramos De Almeida (Fiocruz-RJ, Brazil)
TB003 – Butoconazole as a therapeutic candidate for Chagas disease: experimental evidence against Trypanosoma cruzi
Gabriela Rodrigues Leite Morais (Fiocruz-RJ, Brazil)
HP007 – Endothelial activation and dysfunction drive retinal neurodegeneration and glial scarring through cytotoxic leukocyte infiltration in a clinically relevant mouse model of Ocular Toxoplasmosis.
Vladimir Pedro Peralva Borges Martins (Fiocruz-RJ, Brazil)
TB004 – Modelling the Inflammatory Microenvironment of Localised Cutaneous Leishmaniasis Reveals Cytotoxic Reprogramming of CD4? T Cells
Isabela Valim Sarmento (UCL, UK)
HP008 – Investigating the molecular basis of Trypanosoma cruzi quiescence
Marketa Novotna (LSHTM, UK)
PV004 – Telomere dynamics: understanding the crosstalk between inositol pyrophosphates and telomeres in Leishmania
Vitor Luiz Da Silva (UNESP, Brazil)
11h00 – 11h30 | Coffee break
11h30 – 12h00 | Conference 01 | ROOM A
Chair: Pedro Oliveira
Mosquito midgut response to blood feeding at a single-cell resolution
Ana Beatriz Barletta (NIH/NIAID, USA)
12h30 – 14h30 | Lunch
13h30 – 14h30 | SBPz Council Meeting
14h30 – 16h30 | Round-Tables
RT.01 – Round-Table | Mechanisms of Genomic Plasticity in Trypanosomatids | ROOM A
Chair: Maria Carolina Elias Sabbaga
- From development to transmission: Understanding the development regulation of trypanosomes in the tsetse fly
Lucy Glover (Institut Pasteur, France)
- Deciphering the machineries that guide initiation and progression of nuclear DNA replication in Trypanosoma brucei
Richard McCulloch (University of Glasgow, UK)
- The Cost of Flexibility: Mapping Replication Stress Hotspots and their Impact on Leishmania Genomic maintenance
Luiz Tosi (FMRP-USP, Brazil)
- Mechanisms of Genomic Plasticity in Trypanosomatids
Daniella Bartholomeu (UFMG, Brazil)
RT.02 – Round-Table | Diversity, Ecology and Evolution of Protists | ROOM B
Chair: Daniel Lahr
- Exploring the Hidden World of Protozooplankton in a Neotropical Floodplain: Advances, Current Challenges and Future Perspectives
Felipe Machado (NUPELIA-UEM, Brazil)
- A trait-based approach in ciliate functional ecology: toward a standardized framework
Gabriela Kuppers (MACN-CONICET, Argentina)
- Diversity of microbial communities in aquatic and terrestrial environments
Laura Utz (PUC-RS, Brazil)
- Escaping Ice and Animals: Did Snowball Earth and the Rise of Metazoans Drive Testate Amoebae into Continental Waters?
Luana Morais (UNICAMP, SP, Brazil)
16h30 – 17h00 | Coffee-Break
17h00 – 17h30 | Conferences 02 e 03
CO.02 – Conference | ROOM A |
Chair: Ariel M. Silber
Glycerol metabolism as a novel regulator of trypanosome development and transmission
Frédéric Bringaud (Université de Bordeaux, France)
CO.03 – Conference | ROOM B
Chair: Renato A. Da Matta
TRAMP-CSS complex is essential for hepatocyte and erythrocyte infection by Plasmodium zoites
Daniel Youssef Bargieri (ICB/USP, Brazil)
17h30 – 18h00 |Conferences 04 e 05
CO.04 – Conference | ROOM A
Chair: Yara Maria Traub Cseko
Genomic merger: How Leishmania hybridization drives parasite evolution and immune escape
Gerald Spaeth (Institut Pasteur – Paris, France)
CO.05 – Conference |ROOM B
Chair: Simone Guedes Calderano
Energy status as a signal for adaptation and differentiation in Trypanosoma cruzi
Guillermo Alonso (INGEBI-UBA, Argentina)
18h30 – 19h30 | SBPz Plenary – Ordinary General Assembly | ROOM B
19h30 – 20h30 | Dinner
20h30 – 22h30 | Poster Session – EVEN/Pares | GYMNASIUM
09h00 – 11h00 | Round-Tables 03 and 04
RT.03 – | Vectors|ROOM A
Chair: Alessandra Aparecida Guarnieri
- Effect of Anopheles midgut microbiota bacteria on the sexual development of Plasmodium vivax in Anopheles darlingi
Maisa da Silva Araujo (Fiocruz-Rondônia, Brazil)
- Vitellogenin Receptor Function Shapes Fertility and Microbial Inheritance in Rhodnius prolixus
Isabela Barbosa Ramos (UFRJ, Brazil)
- Trypanosomatids from the Brazilian Amazon: Invertebrate (dipterans) and vertebrate (didelphimorphs, rodents, anurans, squamates) hosts
Claudia Ríos Velasquez (Fiocruz-AM, Brazil)
- Sand fly immunity and gut receptors – implications for Leishmania infection in the vector
Erich Telleria (Charles University, República Tcheca)
RT.04 – | Drivers of Diversity: Kinases, Translation, and the Evolution of Cell Populations | ROOM B
Chair: Luiz Ricardo Orsini Tosi
- Translational Tricks and Trypanosome Tactics
Zdenek Paris (Institute of Parasitology, Czech Republic)
- Gene expression programs driving Leishmania differentiation and transmission in the sand fly
Tiago Ferreira (FMRP-USP, Brazil)
- Cell Cycle Regulation in Trypanosoma cruzi: Conserved Kinases with Parasite-Specific Functions
Simone Calderano (Butantan Institute, Brazil)
- The NEK family in Trypanosoma cruzi: focus on RDK2 in differentiation and host–parasite interaction
Miguel Chiurillo (University of Cincinnati, USA)
11h00 – 11h30 | Coffee break
11h30 – 12h00 | Conferences 06 and 07
CO.06 – | ROOM A
Chair: Juliany Cola Fernandes Rodrigues
From parasite biology to therapy: druggable targets in malaria
Maria Belen Cassera (UGA, USA)
CO.07 – | ROOM B
Chair: Norton Heise
The sweet side of immune evasion in African trypanosomes
Calvin Tiengwe (Imperial College London, UK)
12h00 – 12h30 | Conference 08 | ROOM A
Chair: Otavio Henrique Thiemann
Trypanosomal acetate: succinate CoA transferase: from biochemical and structural characterization to a metabolic engineering tool for bioenergetic studies across organisms.
Daniel Inaoka (School of Tropical Medicine and Global Health – Nagasaki University, Japan)
12h30 – 14h30 | Lunch
14h30 – 16h30 | Round-Tables 05 and 06
RT.05 – | Immunity to Trypanosoma cruzi in the Americas | ROOM A
Chair: Juliana Gomes
- How Trypanosoma cruzi Diversity Shapes Human Immune Responses
Luisa Mourão Dias Magalhães (UFMG, Brazil)
- From Fundamental Research to Public Health: Congenital Chagas in Bolivia
Cristina Alonso-Vega (Universidad de Oviedo, Spain)
- Cellular and Molecular Biomarkers of Cardiac Remodeling: Insights from the Brazilian Scenario of Chagas Cardiomyopathy
Juliana Gomes Estanislau (UFMG, Brazil)
- Stage-dependent adaptation of regulatory T cells during Trypanosoma cruzi infection
Eva Acosta Rodriguez (Universidad Nacional de Cordoba, Argentina)
RT.06 – | One Health | ROOM B
Chair: Ariel M. Silber
- Detection of silent circulation of parasites to ecoepidemiology investigations in a One Health perspective
Marcia Sperança (UFABC, Brazil)
- Insights into trypanosome infection biology from the bovine model
Liam Morrison (University of Edinburgh, UK)
- Zoonotic sarcocystidae: challenges for One Health in protozoology
Aline Diniz Cabral (FCM/Santa Casa de SP, Brazil)
- The Fly That Shaped a Continent: African Trypanosomosis and the Evolution of One Health Solutions
Alec Evans (GalvMed, UK)
16h30 – 17h00 | Coffee break
17h00 – 17h30 | Conferences 09 e 10
CO.09 – Conference | ROOM A |
Chair: Diana Bahia
Mitochondrial butterfly effect: how changes in the organelle physiology impacts the fitness of trypanosomatids
Rubem Menna Barreto (IOC-FIOCRUZ – Brazil)
CO.10 – Conference | ROOM B
Chair: Gerald Spaeth
Benzoxaboroles target CPSF3 for degradation through a SUMO-dependent
Mark Field (University of Dundee, UK)
17h30 – 18h30 | Closing Conference | ROOM A
Chair: Maria Carolina Elias Sabbaga
DNA metabolism in trypanosomatids: why so many differences?
Carlos Renato Machado (UFMG, Brazil)
18h30 – 19h30 | Closing Cerimony, Remarks and Awards | ROOM A
19h30 – 21h30 | Dinner